CBD Oil for Pain Management: Is It Effective?

Cannabidiol (CBD) is a cannabinoid present in cannabis (marijuana and hemp) plants that has no psychoactive effects. Cannabidiol does not produce the so-called “high” sensation that is associated with cannabis.. The chemical that creates those feelings is tetrahydrocannabinol (THC), a separate cannabinoid.

Some clients with chronic pain use topical CBD products, such as CBD oil for pain, to manage their suffering. CBD oil may help to relieve the following symptoms:

  • pain
  • inflammation
  • Perceived overall discomfort as a result of a variety of health conditions

The study of CBD products and pain management has been promising.

CBD has the ability to alleviate chronic pain and dependence on drugs like opioids, which might be habit-forming and result in additional adverse effects. However, more study is needed to confirm CBD oil’s pain-relieving effects and other products’ abilities to treat chronic pain.

Epidiolex, a drug used to treat epilepsy, is the first CBD product to be authorized by the Food and Drug Administration (FDA).

There are no FDA-approved, nonprescription CBD products. They aren’t subjected to the same standards of purity and dosage as other medicines.

Continue reading to discover more about the advantages of CBD oil for pain. You may also talk to your doctor about whether it’s a good fit for your condition.

Chronic Pain Relief

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The endocannabinoid system (ECS) is the body’s cell-signaling mechanism for all species, including humans.

CBD may modulate the ECS’s endocannabinoid system, which includes endocannabinoid receptors in your brain and immune system, according to some researchers.

Receptors are proteins that are attached to cells. They receive communications from a variety of stimuli and assist your cells in responding.

The reaction causes anti-inflammatory and pain-relieving effects that aid in the relief of discomfort. This indicates that CBD oil for pain and other CBD-based treatments can help those who suffer from chronic pain, such as chronic back discomfort.

A 2018 study examined how effectively CBD helps with chronic pain. A review of research published between 1975 and March 2018 was conducted. The following types of pain were studied in these studies:

  • cancer pain
  • neuropathic pain
  • fibromyalgia

Based on these studies, researchers determined that CBD is effective in managing pain and does not produce negative side effects.

CBD for arthritis pain

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CBD oil for pain was studied in rats with arthritis in a 2016 research Trusted Source.

Rats were treated with CBD gel for four days in a row. The rats were given either 0.6, 3.1, 6.2, or 62.3 mg of CBD per day. The scientists discovered that the rats’ afflicted joints had less inflammation and overall discomfort. There were no obvious adverse effects.

Rats receiving low doses of 0.6 mg or 3.1 mg didn’t experience any improvement in pain levels. The researchers discovered that 6.2 mg/day was an adequate dose to alleviate the rats’ discomfort and edema.

Rats that were given 62.3 mg/day had comparable results to those who received 6.2 mg/day, according to the study. They didn’t experience less discomfort as a result of receiving a significantly larger dose.

CBD gel’s anti-inflammatory and pain-relieving properties might help those with arthritis. However, additional research is needed in humans.

Taking a proactive approach, including CBD, may help you calm your symptoms by stimulating the homeostasis mechanism.

CBD oil for pain and cancer treatment relief

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Cannabidiol (CBD) is also employed by several individuals with cancer. CBD has been proven to cause tumor shrinkage in mice. However, the majority of research in humans has focused on CBD’s role in pain management associated with cancer and cancer therapy.

The National Cancer Institute (NCI) has identified CBD as a potential alternative to chemotherapy side effects, including:

  • pain
  • vomiting
  • lack of appetite

In a 2010 research on cancer-related discomfort, participants were given oral sprays of a THC-CBD extract combined with CBD. The THC-CBD extract was used in combination with opioids. The study found that combining the extract with the opioids provided better pain relief than using the narcotics alone.

In a 2013 research on THC and THC-CBD oral sprays, a similar result was found. This study was carried out in collaboration with researchers from the 2010 research. More data is still needed to determine which cannabinoid is more beneficial.

CBD oil for pain and migraines

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There is currently Little to no studies on cannabidiol and migraine. The studies that currently exist also look at CBD when it’s paired with THC, not when it’s used alone.

However, according to a 2017 research, CBD and THC can help people with migraine experience less acute pain and milder pain.

Participants in this two-stage research were given a combination of two substances. The first product was made with CBD and practically no THC. The second compound included 19 percent THC. The treatments were delivered via mouth.

There was no influence on pain in phase I, when the dosages were less than 100 mg. Acute pain fell by 55% when the doses were increased to 200 milligrams.

In the second phase, individuals who were given a combination of CBD oil for pain and THC compounds had a 40.4 percent reduction in migraine attacks. The dose was 200 mg per day.

The combination of compounds was somewhat more effective than 25 mg of amitriptyline, a tricyclic antidepressant, in terms of pain relief. Amitriptyline reduced migraine attacks by 40.1 percent in participants of a study.

Participants with cluster headaches who took CBD and THC together reported pain alleviation, but only if they’d had a history of migraine as a child.

CBD side effects

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Because CBD oil for pain is fat-soluble, it’s unlikely to enter the circulation and cause harm. Most topical CBD products do not reach the circulatory system, and few if any pose significant risks for users.

However, there are certain negative effects that may occur, such as:

  • fatigue
  • diarrhea
  • changes in appetite
  • changes in weight

CBD may interact with a number of medications and supplements, Such as:

  • certain over-the-counter drugs
  • prescription medications
  • dietary supplements

If any of your medicines or supplements include a “grapefruit caution,” proceed with caution. Enzymes that are important to drug metabolism are affected by grapefruit and CBD.

CBD, like other medicines and supplements, has the potential to induce liver damage.

CBD-rich cannabis extract was linked to a higher risk of liver toxicity in one research on mice. However, several of the mice had been fed enormous doses of the CBD-rich cannabis extract via force feeding.


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According to experts, while there is no clear evidence that CBD or CBD oil is the most effective approach for alleviating pain, researchers believe that these types of products have a lot of promise.

CBD oil for pain and other cannabis-based medicines, for example, might be able to provide relief for many individuals with chronic pain while also avoiding drug addiction and dependence.

Talk to your doctor if you’re interested in using CBD for chronic pain. They can assist you in determining a starting dosage that is suitable for you.